Ethan was sent off by his mother to their friendly neighbor Professor Elm. In is lab Elm tells Ethan that his friend Mr. Pokémon has found an egg and that he found. In order go though Ethan needs a Pokémon. So the kind professor lets him choose between Chikorita, Cyndaquil, or Totodile. At Mr. Pokémon's house Ethan gets the Pokédex and a weird egg. Upon leaving Elm calls Ethan and tells him to hurry back to his place. While leaving Cherrygrove City Ethan meets a bully named Silver who stole one of Professor Elm's Pokémon. The two battle and Ethan ends up victorious. Ethan makes it to New Bark Town and informs the cops about Silver. The police depart and Ethan gives the egg to the professor. Elm tells Ethan that he should battle the Gym Leaders from different towns and get Gym badges.
Ethan is the only male player character who does not wear long pants, instead opting for shorts.
Ethan is the only male player character to have two different female counterparts.
Ethan is the main protagonist in Pokémon Puzzle Challenge's Challenge Mode.
The majority of his Japanese default names from HeartGold and Soul Silver are shared with Red and Lucas. The same holds true for their respective female counterparts.
Ethan and Lyra are the only pseudo-rivals, along with the only rival characters in any game apart from Wally, to not appear to have a starter Pokémon from the professor in that region.
Ethan's sprite in HeartGold and SoulSilver is positioned the same as Lucas's in Platinum.
In Gold & Silver version there is a minor trainer named Cal who can be battled in the Viridian City, some fans hinted for the player character would be the default name as "Cal" for the main player character due to the sprite character being the same as Ethan's and because Cal also had only all three level 50 fully evolved Johto starters. However in Pokémon Stadium 2, Cal is a separated character from the player character "Gold", who eventually was renamed to "Ethan".