Solosis is a round, green Pokémon surrounded by a darker green, gel-like substance. This liquid covering allows Solosis to live under any conditions, even in the vacuum of space, but when taking heavy blows, its fluid covering may leak away. Its inner body has dark, oval eyes and a red diamond-shaped mouth. On the upper left side of its head is a curly, yellow growth that resembles the endoplasmic reticulum of a cell. It uses psychic powers to communicate with telepathy, as well as to drive away potential threats.
