The game was noted for several things. First, many lesser-known players would be more powerful than the superstars at the time. Second, teams would become stronger later in the season, contrary to teams wearing out by that time. Third, touchbacks are impossible. Finally, and most infamously, Bo Jackson can easily dominate the field, allowing the player to use him to stiff arm every player while running out the clock entirely.
The SNES version made many major changes. The player stats were corrected. Teams no longer gain strength later in the season. Three seasons can be played instead of one. Team graphics and logos are now displayed. Touchbacks are now possible.